Everything about The Clemmensen Reduction totally explained
The
Clemmensen reduction is a
chemical reaction described as a
reduction of
ketones (or
aldehydes) to
alkanes using
zinc amalgam and
hydrochloric acid. This reaction is named after
Erik Christian Clemmensen, a Danish chemist.
Several reviews have been published.
The Clemmensen reduction is particularly effective at reducing
aryl-
alkyl ketones. With
aliphatic or acyclic ketones,
zinc metal reduction is much more effective.
The substrate must be stable in the strongly acidic conditions of the Clemmensen reduction. Acid sensitive substrates should be reacted in the
Wolff-Kishner reduction, which utilizes strongly basic conditions.
As a result of Clemmensen Reduction, the carbon of the carbonyl group involved is converted from sp
2 hybridisation to sp
3 hybridisation. The oxygen atom is lost in the form of one molecule of water.
Further Information
Get more info on 'Clemmensen Reduction'.
|
External Link Exchanges
Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:
<a href="http://clemmensen_reduction.totallyexplained.com">Clemmensen reduction Totally Explained</a>
Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned. |
